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Clearly the World’s Favorite

 

A breakdown of Aptar Pharma’s Ophthalmic Squeeze Dispenser, showing the bottle, nozzle, and cap components, designed for precise and preservative-free eye drop delivery.

Multidose technology designed for use with preservative-free formulations

Preservatives in eye care formulations, such as Benzalkonium Chloride (BAC), can lead to side effects with chronic use. The Ophthalmic Squeeze Dispenser (OSD) is a leading preservative-free multidose eye dropper worldwide to address this challenge.

The Ophthalmic Squeeze Dispenser’s utilizes a purely mechanical Tip-Seal technology that has been developed for use without preservatives and additives such as silver ions or surface coating.

A close-up of a female with light blue eyes receiving an eye drop from Aptar Pharma’s ophthalmic squeeze dispenser. The drop is about to be dispensed near her upper eyelashes, showing the precision of the eye care dropper.

Tested for microbiological integrity with challenging growth media

Aptar Pharma’s patented Tip-Seal technology has been tested by microbial challenge procedures simulating relevant in-use scenarios (properties of customer formulations require additional testing). We provide a set of data and test methods for the Ophthalmic Squeeze Dispenser which is designed to support pharmaceutical customers in preparing their finished product dossier.

Market References for Eye Care Medications and Consumer Products using Ophthalmic Squeeze Dispenser Technology.

Most accepted technology platform worldwide

The Ophthalmic Squeeze Dispenser is the leading preservative-free multidose technology (PFMD) for both consumer product and prescription eye-care medications, with over 500 market references worldwide and counting.

  • Microbiological Integrity

  • Purely mechanical technology

  • Versatile Platform

  • Convenience

  • Product Stability

  • Easy Filling

  • Established CMO Network

  • Service Packages Available

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Tested for Microbiological Integrity

    Aptar Pharma provides a set of data and test methods for the OSD which is designed to support pharmaceutical customers in preparing the dispensing part of their finished product dossier

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Developed for use with preservative-free formulations

    The OSD has been developed for use without preservatives or additives such as silver ions or surface coating.

    It utilizes a purely mechanical Tip-Seal technology and a filter-membrane. The Tip-Seal prevents backflow into the tip and the sterile filter membrane filters any incoming air when the system is ventilated.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    OSD Technology Platform offers a wide application range for preservative-free eye-care treatments

    Our versatile technology platform offers easy customization solutions for the Ophthalmic Squeeze Dispenser, including color customization to fit branding needs.

    A choice of product features makes our OSD system highly adaptable to specific formulation needs, including prescription medications and over-the-counter products.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Designed to help with convenient and intuitive handling for consumers and patients

    The OSD together with the customer’s selected bottle is designed to provide convenience for on-the-go use as well as to help with convenient and intuitive handling for consumers and patients.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Metal-free fluid pathway and inert packaging materials protect eye‑care formulations

    Inert and safe packaging is particularly important for sensitive eye-care formulations. The OSD’s fluid pathway is metal-free, enabling it to avoid any oxidative reactions of the formulation with ferric metals.

    To protect highly sensitive or reactive formulations, particularly inert plastic materials can be used for the container and the spray pin of the Tip-Seal.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Compatible with existing filling technologies

    The Ophthalmic Squeeze Dispenser can be implemented on existing filling lines and requires no major refitting of production facilities. The OSD’s easy filling process helps to simplify your manufacturing processes.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    A global network of CMOs and CDMOs

    We can connect you to a worldwide network of CMOs and CDMOs that covers a wide range of services: industrial filling at low and high volume, regulatory support, development work and licensing options.

  • A woman with long blonde hair tilts her head back as she uses an ophthalmic squeeze dispenser to apply eye drops. Her hand is holding the small bottle above her eye, preparing to dispense the drops.

    Service packages available to support your product development

    Aptar Pharma provides a set of data and test methods for the Ophthalmic Squeeze Dispenser which is designed to support pharmaceutical customers in preparing their finished product dossier.

Product Details

Flow rates can be specifically adapted to fluid characteristics, e.g. viscosities.

The Pure Pin has a spray pin made from clean COC-material for sensitive formulations to ensure a high level of chemical inertness.

Filter protection valves allow OSD bottle venting via one-way airflow to protect the filter from contact with the medium.

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Pure Cap is hermetically sealed to ensure sterility of the tip prior to first use.

Liner Cap has been designed to avoid crystallization at the tip.

A Standard Cap is also available.

All caps are available in customizable colors.

Selection of third party vendors’ bottle types and sizes suitable for a wide range of formulation needs:

  • Using Soft Bottle option with the OSD helps with easy actuation and optimal flow control.

  • The Pure Bottle is made from ultra-clean COC material to ensure a high level of chemical inertness.

Bottles are available for different volumes.

Bottles are available in translucent or white.

Bottles are available gamma- or ETO-sterilized.

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The Solution is Right Before Your Eyes

Realize your next global eye-care opportunity with our Ophthalmic Squeeze Dispenser.

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15 Mar 2022
An Eye on the Future of Preservative-Free Drops

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