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The Dermal Delivery Solution of Choice for Consumers

 

Man with dark hair and blue sweater dispenses dermal drug product from Aptar Airless+ pump on elbow in office

Want an exceptional user experience for your dermal products? The advanced design of our Airless+ Dermal Drug Delivery systems supports convenient and intuitive operation. Aptar Pharma’s Airless+ systems were designed to always dispense semi-solid formulations cleanly, safely and reliably. And with 360-degree functionality, they consistently deliver a precise dose at virtually any dispensing orientation.

Our Airless+ Dermal Drug Delivery systems minimize product wastage by efficiently dispensing the maximum amount of formulation from the device. The spent dispenser can then be easily recycled, enhancing the user experience while simplifying sustainability.

Aptar Pharma’s Airless+ systems’ advanced functionality makes them the solution of choice for premium Dermal Drug Delivery brands.

Four blue and white Aptar Airless+ dermal dispensing pump systems of different sizes in a row.

Airless+ Dermal Drug Delivery Systems Meet Pharma Requirements

Aptar Pharma’s Airless+ Drug Delivery systems are designed to meet the increasingly strict pharmaceutical regulatory and quality demands for Dermal Drug Delivery systems.
Our Airless+ systems are made with medical grade resins that come with comprehensive change control management, providing transparency to changes in manufacturing processes and materials. We also provide information packages on resin materials and product documentation support for dermal product development and market access. Our Airless+ dermal systems are designed for patient safety and reduced regulatory risks.

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Airless+ Technical and Regulatory Extended Support (ES)

Aptar Pharma’s Airless+ Extended Support (ES) is what we call the industry leading service we offer our customers beyond just devices. Extended Support includes a broad range of world-class technical and regulatory services for your dermal products. Our Extended Support is scaled to meet the needs of your individual product development programs. Test packages are designed for a wide range of semi-solid dermal formulation applications. Device extractables data is generated according to USP/ISO requirements, supporting your product’s leachables study. Our Extended Support services save customers both time and money as the critical information supporting our Airless+ systems are already prepared and available to you. Extended Support is designed to help accelerate and derisk your Airless+ Dermal Drug Delivery programs.

Dermal Drug-Device Combination products

Your Trusted Partner for Dermal Drug-Device Combination Products

Drug-Device Combination product filing requirements are becoming more complex every day. Aptar Pharma’s project and regulatory teams support customers through the latest regulatory filing challenges including US 21 CFR 820.30 or EU MDR 2017/745. Leverage Aptar Pharma’s proven experience in supporting your next Drug-Device Combination product submission. And with Aptar Pharma’s extensive number of combination options, for both visual and functional variations, our Airless+ systems can also help you meet your marketing objectives and increase customer demand.

Airless+ Dermal Drug Delivery Systems Advantages

 

  • Safety and Reliability

  • Derisk and Accelerate

  • Dermal Product Experience

  • Sustainability

  • Man in blue collared shirt opens child resistant cover to Aptar Pharma Airless+ dermal drug delivery device with both hands

    High-level protection of formulations with reliable dosing for consumers

    Our Airless+ Dermal Drug Delivery systems protect your formulation from both light and exposure to external contaminants. Consumers can rely on reproducible and hygienic dosing while the self-closing actuators also prevent drying of sensitive formulations. Our innovative Child-Resistant Senior-Friendly (CRSF) designs help to prevent children from accidentally accessing the product.

    Learn more about Child-Resistant Senior-Friendly (CRSF)
    technology
  • Close up of woman's face dispensing dermal product on elbow from small white Aptar Pharma Airless+ drug delivery system

    Aptar Pharma is your trusted dermal product development partner

    Our Airless+ portfolio offers extensive combination options contributing to brand differentiation, reliably dispensing a broad range of formulation viscosities and is easy-to-fill on existing filling lines. The comprehensive services provided by our Airless+ Extended Support, including ISO/USP tests, and extractables and regulatory filing support, derisks and accelerates your dermal drug development project.

  • Woman in black sportswear seated on sofa applies dermal drug product to shoulder from Aptar Airless+ drug delivery system

    Combining advanced design with convenience

    Our Airless+ dispensing systems are designed to deliver intuitive function, precise dosing, convenience and a superior user experience, all in a premium Dermal Drug Delivery device. Aptar Pharma’s Airless+ Dermal Drug Delivery systems are easy-to-use, providing 360° dispensing for smooth and clean product application. Our dermal devices offer convenient on-the-go solutions for even high viscous formulations.

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    Designed for recycling and sustainability

    Our Airless+ Dermal Drug Delivery devices support your sustainable product objectives with an excellent recyclability, certified by Institute cyclos-HTP. Drive sustainability with the circular economy using a mass balance approach. Our ISCC PLUS certification enables the use of renewable feedstock for our Airless+ systems, without having regulatory or compatibility impact.

Dermal Sustainability

Working Together Towards A More Sustainable Future With Circularity

Our Airless+ dermal device range supports circularity objectives with recyclable packaging
as well as the use of renewable feedstock for Airless+ devices in a mass-balance approach.

 

Sustainable and recyclable dermal devices cyclos-HTP certified Class AAA Certified Mass Balance Approach
  • Designed for Recyclability

    Aptar Pharma’s Airless+ range offers sustainable product features

    Airless+ dermal devices are easy to recycle. The products are only made of recyclable polyolefins and do not include any metal, elastomer or any other materials that would interfere with the recycling stream. With best-in-class evacuation rates, Airless+ devices minimize the amount of dermal product wasted as residue in the emptied devices. They can then be directly recycled without any further effort for the consumer.

  • Certified Recyclability

    Institute cyclos-HTP certified product range

    Our Airless+ product range achieved an excellent recyclability rating of 96% to 98% or “Class AAA” qualification from Institute cyclos-HTP. Institute cyclos-HTP is an independent German institute specializing in the classification, assessment and certification of packaging and goods for recyclability and sustainable product responsibility across Europe. Airless+ can be processed in existing recycling streams across much of Europe including in Austria, Belgium, Germany, France, Italy, Luxemburg, the Netherlands, Norway, Sweden and the United Kingdom.

  • Certified Mass-Balance Approach

    Certified Airless+ production site for renewable feedstock use

    Aptar Pharma’s Villingen production site in Germany holds the International Sustainability Carbon Certification (ISCC) PLUS.  This Airless+ production site supports a fully documented and traceable mass-balance approach along the supply chain, enabling the use of renewable feedstock or bio-based materials in the manufacturing of Airless+ Dermal Drug Delivery systems.

    Learn more about ISCC PLUS Certification on Aptar production sites

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Product Details

 

Our Airless+ Dermal Drug Delivery range includes a variety of dispensing systems using medical grade resins for pharmaceutical use. With numerous functional component combinations and the individual piston positioning service performed by Aptar Pharma, we can supply the widest range of Airless+ devices to the pharmaceutical market.

Our flexible Airless+ Dermal Drug Delivery range provides many dosing options ranging from 200µl to 1500µl combined with container size options ranging from 5ml to 200ml. Airless+ dermal devices, with numerous available actuator and closure designs, can easily deliver brand differentiation.

Our self-closing actuators excel at product protection and prevent drying of the next dose of dermal formulation. Aptar Pharma’s Airless+ range includes both Top- and Bottom-Fill models, providing convenient options for your filling requirements.

Our innovative Child-Resistant Senior-Friendly (CRSF) features prevent accidental product access by minors, while being intuitive and easy-to-use for seniors. Our certified child-protection features have become increasingly important in the growing topical pain treatment, medical cannabis/CBD and rosacea care segments for Dermal Drug Delivery products.

Learn more about Child-Resistant Senior-Friendly (CRSF) technology

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Aptar Pharma’s service and project support makes packaging development easy. We provide comprehensive services, project and technical support through each step of your dermal product development.

From regulatory affairs expertise and specialized filling support to compatibility and functionality testing services, we can help advance your dermal product to market. In addition, we offer responsive collaboration on product concept development, customized marketing samples and mock-ups to keep your project moving forward.

Aptar Pharma’s regulatory affairs experts are up-to-date with current pharma regulations including those for Drug-Device Combination products. Our project teams offer comprehensive DMF support and data on the well-characterized materials. Airless+ Extended Support services provide you with applicable test reports in submission ready formats.

Aptar Pharma’s Drug-Device Combination product support package includes relevant device documentation meeting 21 CFR 820.30 (US) and MDR 2017/745, GSPR (EU) Drug-Device Combination requirements.

 

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Partner With Aptar Pharma
For Your Next Airless+ Dermal Drug Delivery Project

Our Airless+ Dermal Drug Delivery range is fully compliant with current regulatory requirements.
Our support teams can take you from formulation to patient while reducing development risks and increasing speed-to-market.

Request More Information

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Dermal Drug Delivery

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Learn more about Airless Technology

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We Have a Broad Range of Value Added Services to Accelerate and Derisk
Your Drug Product Development.

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